Her six nominations are for Record of the Year ("The Joke"), Album of the Year (By the Way, I Forgive You), Song of the Year ("The Joke"), Best American Roots Performance ("The Joke"), Best American Roots Song ("The Joke") and Best Americana Album (By the Way, I Forgive You).
The music world will hit the red carpet on Sunday for the Grammys, with a wider selection of nominees - led by hip-hop royalty and a bevy of talented women - up for the top prizes. They were also nominated for Best Recording Package for Love Yourself: Tear.
The opening contrasted with last year's Grammys, where male acts dominated in nominations and the only woman competing for the top award, Lorde, didn't get a chance to perform onstage.
"It was when my creativity & self expression was stifled by you, that i decided not to attend. i hope the show is exactly what you want it to be and more", she continued.
The Grammy Awards kicked off Sunday with a group of powerful women, including Michelle Obama and Lady Gaga, describing the role of music in their lives - a display that came a year after female voices were somewhat muted at the 2018 ceremony.
"It's our first time ever presenting an award, and also the Grammys so... yeah I stayed up all night", he added.
They are both up for album of the year, alongside Cardi B, H.E.R., Post Malone and Janelle Monae. "As much as it is about me, it's not just about me", said Monae, who gave a powerful speech previous year ahead of Kesha's emotional and striking performance celebrating sisterhood and women's rights. "Thank you for being my island", she said.
An absent Ariana Grande, who pulled out of the show last week after a dispute with producers, won her first Grammy, best pop vocal album for "Sweetener".
Keys told CBS news this year´s greater representation from women was "far overdue".
Top nominees Gaga, Monae, Cardi B, Carlile and country star Kacey Musgraves are all due to take the stage at the Staples Center.
This year's show exhibits some efforts to combat these diversity issues - the academy, which The Times reported has invited 900 new members to vote, expanded major categories from five to eight nominees. Yolanda Adams, Fantasia and Andra Day will honour the late Aretha Franklin with a performance.