Uruguay's defence might be a bigger problem for Ronaldo and Portugal when the teams meet in Sochi. Tabarez had devised his successful tactical system at a time when Uruguay did not boast of quality central midfielders, but the emergence of the likes of Vecino and Bentancur has comforted the veteran manager.
Uruguay are hopeful Jose Maria Gimenez will return from injury to resume his centre-back partnership with Atletico Madrid team-mate Diego Godin.
But while Pepe and Cristiano Ronaldo will look to get one over La Liga rival Suarez, the forward showed he had a spring in his step during sprinting drills on Friday. That miss, however, has probably fired the 33-year-old to come up with a stronger display in this encounter.
"We will mark him with the same respect we mark everyone, despite him being a superstar", said Sebastian Coates of Ronaldo.
"We are going to have to work collectively". And the Portuguese have proved adept at long-range strikes-scoring three times from outside the area-while four of the South Americans' five goals in Russian Federation have come from set pieces, per WhoScored.com.
"Considering the limitations we have as a country in footballing terms, we have come into this World Cup just as we wanted and in the three games we have played so far I think we are closer than ever to what we want to be".
What's the latest news on the two teams?
Perhaps ominously for Uruguay - and the rest of the teams remaining in the tournament - Cristiano Ronaldo, the crown prince of Portuguese football, appears in top form and has arguably been the best player in the tournament thus far, though his side won just one of the their three group games.
I expect a tough and very physical match with a penalty shootout to determining the winners of this match.
- Luis Suarez has scored seven World Cup goals for Uruguay, second only to Oscar Miguez (eight) - Suarez scored a brace against South Korea in his only previous appearance in the round of 16 back in 2010. Excelling in their man-management skills, they surely have the strategic know-how and they have already led their sides to continental glory; and simply an iota of sparked brilliance could decide the game today. I've told them they need to be calm.
Unlike Messi, Ronaldo has led Portugal to an worldwide title, the 2016 European Championship, and at 33, the fanatically well-conditioned player still appears to have the physical gifts of his youth.